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Work with a clinician or counselor to map a timeline of likely stages: immediate post-op swelling, mid-term changes as tissue settles, and long-term results once healing is complete

For the primary composite outcome and secondary hierarchical outcomes, the threshold for two-sided statistical significance was set to 0.0322 (one-sided level 0.00161) using Lan-DeMets alpha spending function, which allows to adjust significance levels as data were reviewed for the interim analysis, reducing the chance of false positive results

Alle data are presented as n (%)

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WHO: World Heath Organisation

Third, individual responses to GLP-1 class drugs vary some people are biologically more responsive than others