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142 Inflammatory mediators from pyroptosis also impair insulin signaling, increase insulin resistance, and upregulate lipid synthesis genes, contributing to hepatic lipid accumulation

Glutathione can modulate and reverse this suppression

*Correspondence: Jesse Roth, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Technical Challenges Oxidative Degradation: The peptide degraded within 14 days under standard accelerated aging conditions (40C)