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doi: 10.1021/acsami.8b20594 265 WangJ.SongY.ChenZ.LengS

B12 does not store like some other vitamins

We know that on average, for every 1kg people lost whilst on Wegovy, approximately 0.3kg was muscle, and 0.7kg was fat

However, other studies have demonstrated positive associations between gluteofemoral SAT and IS in humans, including a slower rate of lipolysis, a lower proinflammatory response, and increased secretion of insulin-sensitizing adipokines [30]

For instance, while GLP-1 agonists are primarily metabolised by the kidneys and have a low potential for significant drug-drug interactions, it is still important to monitor patients closely when combining therapies

Rambeck B, Wolf P