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Novel therapy of bicarbonate, glutathione, and ascorbic acid improves cystic fibrosis mucus transport
Such mechanisms enable precise control over therapeutic delivery, where, for instance, pH-sensitive linkages break down in acidic environments to release payloads directly at infection sites, or ROS-triggered oxidation facilitates burst release of antimicrobials
10.1093/pcp/pcn007 Plant Cell Physiol
In addition, single-cell transcriptomic analysis of a mouse model of hepatic ApoE3 knockout revealed that hepatic ApoE3 significantly upregulates genes associated with cell adhesion, synaptic plasticity, and carbohydrate metabolism [88, 90]
Last updated: 2026-02-26
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