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Niraparib showed promising activity in preclinical models and phase I clinical trials, achieving its pharmacodynamic target for PARP inhibition in epithelial ovarian cancer, particularly in patients who have responded to platinum-based chemotherapy 167 (Fig

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The inclusion of benzyl alcohol provides a self-preserving formulation that inhibits microbial growth following initial puncture of the vial, permitting multiple withdrawals over a defined period of time a characteristic that distinguishes it from single-use sterile water for injection products typically encountered in laboratory supply catalogs

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U., Fusar-Poli, P., Croatto, G., Carvalho, A