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Liraglutide (Saxenda) was given to participants initially with a dose of 0.6mg daily and titrated up to the therapeutic dose of 3.0mg daily by an increase of 0.6mg per week (the usual dose for this medication)

The animal housed individually in stainless steal cages under controlled condition at constant temperature (22C) and lighting (12 light-dark cycle) and given free access to food and water at all times

May contain hydrochloric acid for pH adjustment. The bacteriostatic saline for injection solution's pH is 5.0 (4.5 to 7.0)

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