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Global demand for GLP-1 receptor agonists is expected to be driven by rising rates of diabetes and obesity
Bishop NA, Lu T, Yankner BA (2010)
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For instance, when there is an influx of Ca 2+ in pancreatic cancer cells, specific subunits of ESCRT-III, referred to as CHMPs (charged multivesicular body proteins), particularly CHMP5 and CHMP6, are recruited and assembled at the damaged site, actively contributing to the restoration of membrane integrity in liver and pancreatic cancer cells [143]