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J Mol Endocrinol (2020) 64(2):10313

Early intervention is equally essential that is something I have learned through caring for these patients over the past several years

New retatrutide data raise the ceiling for what next-generation metabolic drugs may eventually achieve, but investigational results should not be confused with an available treatment plan

As of 2022, GLP-1RAs have been recommended as first-line treatments, along with SGLT-2 inhibitors, for patients with T2DM and cardiovascular disease in American Diabetes Associations Standards of Medical Care in Diabetes (248, 249)

Consult your clinician about the risks and benefits of any treatment

Clinical interest has focused on GLP-1 as GIP is no longer active in Type 2 diabetes