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Upregulation of MMP12 and its activity by UVA1 in human skin: potential implications for photoaging

[9] GST-Pi is expressed in many human tissues, particularly in the biliary tree, renal distal convoluted tubules and lungs

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The induction of oxidative stress and inflammation at the maternalfetal interface leads to activation of the NLRP3 inflammasome (119121)

The present study hence focused on compounds, already in clinical use, with the potential to activate the Nrf2 stress response pathway

Patient-specific lipid profiles should thus be considered when formulating and delivering cholesterol-conjugated aptamer treatments in order to provide clear therapeutic recommendations (143)