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Eating within a defined 8-10 hour window, combined with protein-forward meals and adequate fiber, naturally reduces calorie intake without relying on pharmaceutical hunger suppression

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Cardiovascular outcome trials that are planned or underway will determine whether such robust cardiometabolic potency through complementary receptor targeting translates into incremental cardiovascular protection, ideally with improved drug tolerability

Common side effects include nausea, vomiting, constipation, and loss of appetitemost mild and temporary during the dose-escalation phase

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