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Topical injections of recombinant HGF have been successfully employed in many animal models of neurological diseases

And a lot of our audiences had braces as kids, probably had teeth pulled, myself included

J Biol Chem 283(1):38897 Greendale GA, Witt-Enderby P, Karlamangla AS, Munmun F, Crawford S, Huang M et al (2020) Melatonin patterns and levels during the human menstrual cycle and after menopause

The trial program has evolved from glycemic-safety and outcomes studies in T2D (the LEADER, SUSTAIN-6, REWIND, EXSCEL, and PIONEER 6 era [10][13], [19]), to outcomes trials in expanded populations including obesity without diabetes (SELECT [3]), HFpEF with obesity (SUMMIT [5], with a companion semaglutide program in STEP-HFpEF [20], [21]), CKD (FLOW [22]), and an active-comparator setting (SURPASS-CVOT [6])

doi: 10.1016/S0140-1963(18)31366-1 172 MndzebeleB.NcubeB.NyathiM.KanuS