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Introduction Obesity is a chronic complex disease contributing to the development of various obesity-related comorbidities, such as metabolic syndrome and dysfunction, type 2 diabetes, cardiovascular diseases, depression, and certain cancer forms [1]

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Certain bacterial antigens share structural similarities with thyroid autoantigens, such as TPO and thyroglobulin, leading to the production of cross-reactive autoantibodies like TPOAb and TgAb (Xu et al., 2021)

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