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Its activity intersects two major metabolic pathways simultaneously: the NAD+ biosynthesis pathway (by consuming nicotinamide, an NAD+ precursor, NNMT competes with the NAD+ salvage pathway) and the methyl-donor pathway (by consuming SAM, NNMT reduces the availability of methyl groups for epigenetic and metabolic methylation reactions)

I even tried to get livestock methyl cobalamin, because I do have situations where B12 and iron injections become necessary

How The Body Handles Excess B12 As mentioned above, vitamin B12 is a water-soluble vitamin

There is also the slight risk of nerve injury with IM shots

Vitamin B12 Is Essential B12 is an essential vitamin, which we typically get through our diet