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Multiple animal and cell-culture studies have shown that when renal glutathione is experimentally depleted, tubular cells become significantly more vulnerable to injury from toxins, ischemia, and oxidative stress reinforcing that adequate glutathione is protective for kidney tissue, not threatening to it

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Abstract Fabry disease is an X-linked lysosomal storage disease caused by a mutation in the galactosidase alpha (GLA) gene

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Initial protocols commonly run six to twelve weeks, with longer courses for complex or chronic cases and maintenance schedules afterward where appropriate