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Weight loss is sustained while patients remain on incretin treatment

When comparing phentermine vs semaglutide, the STEP 1 trial reported that participants who stopped semaglutide medication after 68 weeks regained roughly two-thirds of their lost weight within one year

Abnormal estrogen signaling through ER is a major driver of tumorigenesis in luminal A and luminal B breast cancers [4], as it promotes the proliferation of cancer cells by overexpressing cyclin D1 and c-Myc, both of which enable the tumors to bypass the G1/S checkpoint [5]

That's one of the reasons why both are found in Guards Up

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Your provider may recommend staying at your current dose longer, reducing back to a previous dose, or switching to a different compound