The first ADC for treatment of solid tumors was Ado-Trastuzumab Emtansine (Kadcyla ) or T-DM1 for treatment of HER2+ metastatic or locally advanced breast cancer and was approved in 2013 (162)
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Funding This study was financed in part by the Coordination of Improvement of Higher Education Personnel (CAPES) BrazilFinance Code 001
