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This transition is accompanied by upregulation of fatty acid oxidation genes (such as CPT1 and ACADVL) and downregulation of key glycolysis enzymes [258, 259]

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Cryogenic electron microscopy data indicate that at least for the echovirus serotype 6m, polar interactions between the 2 domain of FcRn and proteins in the viral coat may enable a viral association with the receptor at the cell surface and trigger endocytosis and a pH-dependent destabilization of the viral particle