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The activation of this complex induces the self-cleavage of pro-caspase-1 into active caspase-1, which then undergoes a site-specific hydrolysis of pro-IL-1 to generate mature IL-1, thereby activating the related signaling pathways to mediate the inflammatory cascades (40, 54)

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3.3 SMOTE techniques performance To address the class imbalance in the dataset, the diagnostic performance of five ML models (LR, DT, RF, GBoost, and KNN) was assessed using different SMOTE techniques, including Borderline-SMOTE, SMOTE-ENN, and adaptive synthetic sampling (ADASYN)

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If hunger persists despite adequate smoothie nutrition, discuss it with your provider, as it may indicate a need for dose adjustment