It is noteworthy that such delivery challenges are not unique to SFN but represent a common hurdle for many bioactive phytochemicals, as comprehensively documented in the case of curcumin where nano-formulations have successfully addressed similar bioavailability limitations
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Kurokawa T et al
Future research should integrate longitudinal population studies, mechanistic experiments, and circadian rhythm assessments to determine whether prolactin should be considered a driver, regulator, or biomarker of obesity-related metabolic disorders, thereby providing a theoretical basis for more refined and individualized clinical strategies
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