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The trial evaluated retatrutide as an adjunct to diet and exercise in adults with type 2 diabetes and inadequate glycemic control

GLP-1 medications are a great option for many people, but they aren't right for everyone

Patients should seek immediate medical attention for severe abdominal pain (possible pancreatitis), persistent vomiting leading to dehydration, or symptoms of significant hyperglycemia

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The widespread distribution and function of multiple GLP-1 receptor populations in the central and autonomic nervous system provide the anatomical foundation for the appetite-suppressing effects observed with GLP-1 agonist therapy

PMID 26500843