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Inhibition of SLC2A1 using small-molecule inhibitors like STF-31 can reduce glucose uptake and alleviate T cell exhaustion [108, 109]

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Skin Thinning (Skin Atrophy) Prolonged steroid use breaks down collagen, causing: Extremely thin, fragile skin Visible veins Easy bruising and tearing Once thinning occurs, the skin may never fully recover

This is why glutamine is often considered conditionally essential

In neurodegenerative conditions, it leads to neuronal damage and cognitive decline