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Injecting air into the vial during draws creates positive pressure that can force contaminants back through the needle on subsequent draws

Whereas sporadic and NF1-associated malignant peripheral nerve sheath tumors showed a comparable frequency of loss of H3K27 trimethylation (72% vs 71% respectively), all radiation-associated malignant peripheral nerve sheath tumors ( n =4) exhibited loss of H3K27me3 expression