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Needle size depends on the viscosity of the liquid being injected (Dougherty and Lister, 2015)

doi: 10.1016/j.metabol.2021.154838 31 OppertJ-MCianguraCBellichaA

Armaly Z, Abd El Qader A, Jabbour A, et al

Many patients notice that semaglutide naturally reduces appetite within hours of injection, so planning lighter meals or smaller portions during the first few days after your weekly dose may help you adapt to this effect

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