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When used concurrently with insulin or insulin secretagogues such as sulfonylureas or meglitinides, the risk of hypoglycemia may be increased, particularly during the initiation of therapy or following dose escalations

SGLT1 is expressed in several tissues, with highest levels of expression in the small intestine where its primary function is in glucose and galactose absorption

They act as protective carriers that help sensitive nutrients stay intact until they reach the body

Korkmaz, F

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It has been also reported that selenium may regulate the inflammatory response by reducing the release of tumor necrosis factor (TNF) and cyclooxygenase (COX2), as well as the activation of nuclear factor B (NF-B) which is one of the transcriptional factors involved in the immune and pro-inflammatory response