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Further translational research and prospective clinical trials are required to clarify causality, determine effect size, and identify high-risk groups most likely to benefit

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Allergic reactions In the same trial, 3-13% of patients had allergic or hypersensitivity reactions in the retatrutide group and 3% in the placebo group

For some people, this combo makes eating enough difficult, which can affect nutrition, mood, and medication tolerance

So identifying the reason is important