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This includes the production of numerous pro-inflammatory cytokines such as TNF- and pro-IL-1 and chemokines which induce signaling cascades that promote the differentiation of FLS into myofibroblasts via auto- and paracrine signaling (169)

( C ) DPP4 activity, ( D ) soluble DPP4 concentration, ( E ) active GLP-1, ( F ) active GIP, ( G ) insulin, and ( H ) glucagon from the PV and CP 15 minutes after glucose bolus in Dpp4 GFP ( n = 412) and Dpp4 hep/ ( n = 411) mice

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doi: 10.1080/2162402X.2019.1633235 129 WangJ

GLP-1 medications are not suitable for everyone