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Understanding those differences is what separates informed decision-making from guesswork

TRIUMPH-1 is the flagship obesity trial, targeting adults with a body mass index (BMI) of 30 or greater, or a BMI of 27 or greater with at least one weight-related comorbidity such as hypertension, dyslipidemia, or obstructive sleep apnea

[DOI] [PMC free article] [PubMed] [Google Scholar] 95.Marso SP, Nauck MA, Monk Fries T, Rasmussen S, Treppendahl MB, Buse JB

Mixing these two categories, particularly without robust scientific backing and clinical supervision, introduces an unacceptable level of risk

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Siddeeque N, Hussein MH, Abdelmaksoud A, et al