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Diarrhea A frequent gastrointestinal side effect

After two years, patients using it still benefit by not regaining their lost weight but only if they are still taking the drug

But its GI side effect profile is also the most aggressive, with nausea rates reaching 40% to 50% and vomiting rates significantly higher than cagrilintide monotherapy

This disciplined approach maintains consistent absorption across all injection events, supporting stable weight loss progress and reducing the risk of localized complications

In certain formulations, B12 is added to compounded semaglutide to enhance energy or support weight loss, but its potency isnt always consistent