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reported that in the radial maze test, where the first entry but not the repeated entries to each arm were rewarded by food, Lurcher mice made more repetitive arm entries, counted as incorrect responses, than WT mice [171]

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Zhang and others discovered that Polygonum sibiricum polysaccharides (PSP) were capable of elevating serum levels of 5-HT and NE, reducing pro-inflammatory cytokine levels in the hippocampus, as well as inhibiting the PI3K/AKT/TLR4/NF-B and ERK/CREB/BDNF pathways in mice with depression induced by CUMS (Zhang et al., 2023)