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Iron-mediated oxidative damage in ferroptosis Iron as a cofactor is important for maintaining a range of biological processes [48]

Interestingly, we noticed that the bile biosynsthesis-related biological processes were largely enriched, as determined in the catergory of molecular function, suggesting that Cori might restored the dysregulated BA metabolisms mainly caused by hepatic lipid accumulation in livers of mice with HFD feeding ( We also conducted a visualized PPI network using the overlapped DEGs, which facilitated to discover the Cori-dependent hub proteins (namely putative targets) in livers regulating NAFLD

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