When your body has enough insulin, your blood sugar levels stay balanced
The challenge is to get these results into clinical practice, to get the drug used by the people who will benefit from it, who will live longer without dialysis, without heart attacks, without strokes, if they take this drug. Novo Nordisk will need to seek regulatory approval for semaglutide to be used to treat those with chronic kidney disease
In essence, while orlistat's role in weight reduction is established, its associated gastrointestinal adverse effects present significant hurdles in clinical practice
These observations point to a cross-talk between circulating GLP-1 and the brain, but the relative importance of peripheral versus central GLP-1 for the control of glucose homeostasis is not known
Track and adjust
Arnhem, The Netherlands: European Association of Urology Guidelines Office