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Vigorous shaking can increase the risk of introducing contaminants into the vial, compromising the sterility of the solution and potentially leading to adverse reactions

Cellular senescence was assessed by measuring senescence-associated -galactosidase (SA--gal) activity using a commercial staining kit

Both are within the 28-day stability window

Side effects are rare but may include minor bruising at the injection site or mild nausea

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Wang and Gu, 2014), c-Jun/AP-1 (Marshall et al., 2000), NF-B (Pineda-Molina et al., 2001), heat shock factor 1 (HSF1