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What happens when the leptin receptor has a mutation

doi: 10.1016/j.mce.2014.07.021 95 CrakeRGasmiIDehayeJLardinoisFPeifferRMaloujahmoumNet al

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We found a pronounced inhibitory effect when opening K ATP -channels while stimulating with l-valine in the perfused rat small intestine, suggesting that changes in the membrane potential of GLP-1 secreting L-cells may play a crucial role in l-valine induced GLP-1 secretion

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In contrast, the primary ligands of CD36 on oxLDL appear to be oxidized phospholipids, in particular fragmented phosphatidylcholine including azPAF (243), POVPC (343) and KOdiA-PC (280)