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IV-administered glutathione is where the majority of human clinical data exists, with modest evidence from small trials in Parkinsons disease showing some symptomatic benefit (though results have been inconsistent and have not been replicated at scale)

The $10 billion price rested on optimistic assumptions about Metseras future performance, estimating Pfizer would need to generate about $11 billion in revenue from the deal by 2040 nearly double Metseras current projections, Courtney Breen, an analyst at Bernstein, said

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Latremoliere A, Costigan M

"Concise review of the glutathione S-transferases and their significance to toxicology"