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These results suggest that a tapering regimen of GC therapy could be an alternative without the loss of efficacy in patients with SAH

Future studies should explore the dynamic interactions among SIRT1, mTOR, autophagy, and endoplasmic reticulum (ER) stress to elucidate its regulatory functions under varying metabolic states, guiding the development of targeted interventions for early-stage MASLD-related metabolic disorders

They are also shown to be used for the treatment of cancer, as well as in the treatment of cystic fibrosis, rheumatoid arthritis, acne, and psoriasis

Instead, both these activities are provided by selenocysteine (Sec/U)-containing thioredoxin glutathione reductase (TGR) 16

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