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Lys105 has a dual function for the oxidative and reductive half-reaction of ScGrx7 resulting in a decrease of all k cat app , k cat app / K m app and 1/ values for K105A/Y/E (Fig

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Induction of mGlu2 receptors is mediated by acetylation mechanisms that involve transcription factors of the nuclear factor (NF)-B family

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Such pulsatile signaling resulting from intermittent release of GHRH from neurosecretory hypothalamic neurons consistent with prior and concurrent hypothalamic somatostatin tone preserves biosynthesis and secretion of somatotropin