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Additionally, the amenability of PLGA nanosystems to functionalization by ligands (lactoferrin) or polymers (PEG) could facilitate targeted delivery, ensuring efficient delivery of their cargos to target tissues and thus minimizing off-target effects 31

doi: 10.1038/s41380-024-02526-4 56

Finally, we used to model to show how the observed metabolic profile of Down syndrome could arise from trisomy 21 and moderate oxidative stress and how the observed metabolic profile of autism patients could arise from high oxidative stress and increased adenosine concentration

Endocrinology 135 , 20702075 (1994)

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Intravenous Dosing Limited studies have evaluated NAD+ for conditions such as Parkinsons Disease