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Other potential mtDNA sensing pathways Beyond the well-characterized cGASSTING pathway, accumulating evidence indicates that additional cytosolic DNA sensors may recognize mtDNA and contribute to innate immune activation, although their specific roles within the CNS remain incompletely understood

This makes it a unique and popular choice within neurological and behavioral research

Retrieved from Liu, X., Li, Y., Tobias, D

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Ageing alters behavioural function and brain arginine metabolism in male SpragueDawley rats