SorliCHarashimaSITsoukasGMUngerJKarsblJDHansenTet al
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If you have reached the maximum dose of semaglutide (2.4mg) and are no longer seeing improvements in your A1C or weight, tirzepatide may be the logical next step
Its concentration is particularly high in mitochondria, where it protects respiratory chain complexes from oxidative stress (Wu et al., J Nutr 2004)
Patients should focus on nutrient-dense, lower-calorie foods emphasizing lean proteins, vegetables, whole grains, and healthy fats