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Pregnant and nursing individuals should also consult their healthcare professional before using glutathione supplements

Acknowledgments Biorender.com was used in the preparation of Figures 1 , 2

In addition, adipose tissue secretes proinflammatory cytokines, including tumor necrosis factor- (TNF-) and interleukin-6 (IL-6), which may impair neuromuscular control and exacerbate nocturnal respiratory instability (9, 10)

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A recent study showed that the accumulation of UA in DNA-damaged tumors activates TAK1 and its downstream kinases, JNK, and AMPK, to phosphorylate ULK1 S555 and initiate autophagy [215](Fig

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