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The general principle with copper peptides is that excessive application can break down tissue faster than regeneration occurs, so more is not always better

Braz J Med Biol Res 49(12):e5826 Dokken BB, La Bonte LR, Davis-Gorman G, Teachey MK, Seaver N, McDonagh PF (2011) Glucagon-like peptide-1 (GLP-1), immediately prior to reperfusion, decreases neutrophil activation and reduces myocardial infarct size in rodents

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Draw air into the syringe equal to your dose volume, insert the needle through the stopper, push the air in, then invert the vial and draw out your prescribed dose

Temperature fluctuations from opening and closing your refrigerator door are normal and do not harm the medication