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Key Points Highlights: The study identifies peptides with abnormal expression in Ovarian endometriosis (OvE), thus that researchers can better understand the pathogenesis of the disease

The researchers found that within the first 24 hours of administration, the urinary excretion of arsenic increased significantly by 130%

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Burgold et al., 2008)

From the perspective of pathophysiology, PD shows obvious inflammatory response

Therefore, clonidine therapy must always be tapered gradually over a minimum of 2 to 4 days (or weeks for higher doses), and any concurrent beta-blockers must be discontinued several days prior to beginning the taper (JAVADIN, 2025