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Buyer Takeaway: The side-effect profile for a botanical adhesive patch is generally low-risk for most adult users - the main variable is interaction with prescription medications

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Conclusions The present review elucidates the physiological benefits of synthetic incretin-based medications, highlighting both their unprecedented clinical efficacy against T2D and obesity and their extensive non-target metabolic benefits against heart, kidney, and liver diseases

Lancet (1999) 353(9167):18659

Study design ATTAIN-MAINTAIN enrolled participants who had already completed 72 weeks of treatment with the highest tolerated doses of either semaglutide (Wegovy) or tirzepatide (Zepbound) as part of the SURMOUNT-5 trial