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Performing several roles within the body, B12 supports the normal function of nerve cells and plays a vital part in the synthesis of red blood cells and DNA

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The 4-hydroxy-2-nonenal (HNE) is the most sensitive marker

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These findings reinforce the value of multimodal baseline profiling, integrating biochemical and retinal imaging biomarkers, to identify patients at higher risk of early disability progression and to support more personalized management strategies in MS