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In fact, in GLUTag cells, we showed that L-glutamine enhanced GLP-1 secretion and cAMP accumulation, suggesting that L-glutamine stimulates GLP-1 secretion by activating Gs-coupled receptors such as TAS1R3 28

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Semaglutide is a GLP-1 receptor agonist, meaning it mimics the activity of a naturally occurring gut hormone called glucagon-like peptide-1 (GLP-1)