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Phase II data (NEJM, 2023) showed up to 24.2% mean body weight reduction with Retatrutide at 12mg weekly over 48 weeks, compared to approximately 21% with Tirzepatide at 15mg in the SURMOUNT trials over comparable periods

Separating evidence from hype requires looking at the actual studies, their limitations, and what they do and do not prove

Patients can expect to lose a significant percentage of their body weight when combined with lifestyle changes

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Ro charges a $39 membership plus medication cost (typically $149/mo for the membership tier on annual, plus the medication itself either compounded options or branded Wegovy/Zepbound at retail or self-pay), per Ros published rates as of April 2026

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