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Over time, patients may notice steady weight reduction as the body adjusts

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Correction (4/2): This article has been updated to reflect that Foundayo is the brand name for orforglipron.

What We Know So Far The clinical trials that established the safety and efficacy of GLP-1 medications, including the STEP and SURMOUNT trial programs for semaglutide and tirzepatide, respectively, enrolled predominantly middle-aged adults

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