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For MACE-4, the HR was 0.80 (95% CI, 0.571.11) for tirzepatide versus standard therapy, the HR for cardiovascular death 0.90 (95% CI, 0.501.61) and 0.80 (95% CI, 0.511.25) for all-cause death
An oral alternative that works as well as or better than existing options, and can be taken as easily as a daily vitamin, has the potential to meaningfully expand access
Overall, though, its a reliable choice for those looking for a wallet-friendly option
Metformin, one of the most widely used diabetes drugs, has also been studied for its potential to protect the brain and reduce dementia risk
Parkinsons, Alzheimers and other researchers are embedding nanoparticles of drugs in a substance called chitosan (a biodegradable, biocompatible polymer) which can adhere to mucous membranes in the nose and release much more of the drug much deeper into the brain than aerosolized preparations do
They contain good stability to bio deterioration
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