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Zero-calorie and zero-sugar drink, sweetened with sweeteners and enriched with 0.5% cranberry and lemon juice from concentrate

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Clinical investigations suggest that the cerebrospinal fluid (CSF) levels of HMGB1 in patients with subarachnoid hemorrhage (SAH) demonstrate a positive correlation with proinflammatory factors, such as IL6 and TNF, and that the degree of HMGB1 elevation is closely related to the severity of the disease [353]