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Why this matters: Injecting water forcefully onto the dry powder generates foam, creates mechanical stress on the peptide chains, and can reduce potency

Participants were randomly assigned 2:1 to once-weekly semaglutide or placebo plus standard of care for 72 weeks

If you want a broader overview of this treatment class, our guide to GLP-1 therapy and how it supports weight loss is a helpful place to start

Both medications contain semaglutide, but the dosing and absorption differ, affecting overall effectiveness for weight reduction

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The first three amino acids that are emitted are Gly-Pro-Glu which are removed through the N-terminus